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Tadalafil (Cialis) is taken by mouth either as needed before sexual activity or once daily for erectile dysfunction (ED). It’s also taken once daily to treat symptoms from an enlarged prostate (benign prostatic hyperplasia, or BPH). Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include headache and indigestion. Tadalafil (Cialis) does interact with some medications, such as heart and blood pressure medications, and taking them together could lead to very low blood pressure and dizziness.

What is tadalafil (Cialis)?

How tadalafil (Cialis) works

Tadalafil (Cialis) is a phosphodiesterase-5 enzyme (PDE-5) inhibitor. It works by blocking PDE-5. This is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks PDE-5, tadalafil (Cialis) helps an erection occur by allowing certain muscles in the penis to relax and the penis to fill with blood.

While it’s not fully clear how tadalafil (Cialis) helps treat symptoms of BPH, researchers think it helps relax the muscles in the prostate (a small gland in the groin).

What is tadalafil (Cialis) used for?

Erectile dysfunction
Benign prostatic hyperplasia (BPH)

Tadalafil (Cialis) dosage forms

Tablet

20mg

Typical dosing for tadalafil (Cialis)

Erectile dysfunction (taken as needed): The typical starting dose is 10 mg by mouth about 30 minutes before sexual activity up to once per day as needed. Your provider will adjust your dose based on your response.
Erectile dysfunction (taken daily): The typical starting dose is 2.5 mg by mouth at the same time every day, without regard to timing of sexual activity. Your provider will adjust your dose based on your response.
Benign prostatic hyperplasia alone or with erectile dysfunction: The typical dose is 5 mg by mouth at the same time every day.